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Effector CD4 T cell transition to memory requires late cognate interactions that induce autocrine IL-2
It is unclear how CD4 T cell memory formation is regulated following pathogen challenge, and when critical mechanisms act to determine effector T cell fate. Here, we report that following influenza infection most effectors require signals from major histocompatibility complex class II molecules and...
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| Publicado no: | Nat Commun |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4223689/ https://ncbi.nlm.nih.gov/pubmed/25369785 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms6377 |
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