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Distinct roles for IL-2 and IL-15 in the differentiation and survival of CD8(+) effector and memory T cells

Interleukin-2 (IL-2) provides a memory differentiation signal to CD8(+) T cells during the primary response that impacts the ability of the subsequent memory pool to mount a successful recall response. We find here that while primary effector CTL development is modestly decreased in the absence of I...

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Autori principali: Mitchell, Diana M., Ravkov, Eugene V., Williams, Matthew A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2950111/
https://ncbi.nlm.nih.gov/pubmed/20483725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0904089
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