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Distinct roles for IL-2 and IL-15 in the differentiation and survival of CD8(+) effector and memory T cells

Interleukin-2 (IL-2) provides a memory differentiation signal to CD8(+) T cells during the primary response that impacts the ability of the subsequent memory pool to mount a successful recall response. We find here that while primary effector CTL development is modestly decreased in the absence of I...

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Detalhes bibliográficos
Main Authors: Mitchell, Diana M., Ravkov, Eugene V., Williams, Matthew A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2950111/
https://ncbi.nlm.nih.gov/pubmed/20483725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0904089
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