Increased IL-15 Production and Accumulation of Highly Differentiated CD8(+) Effector/Memory T Cells in the Bone Marrow of Persons with Cytomegalovirus

Cytomegalovirus (CMV) has been described as a contributor to immunosenescence, thus exacerbating age-related diseases. In persons with latent CMV infection, the CD8(+) T cell compartment is irreversibly changed, leading to the accumulation of highly differentiated virus-specific CD8(+) T cells in th...

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Udgivet i:Front Immunol
Main Authors: Pangrazzi, Luca, Naismith, Erin, Meryk, Andreas, Keller, Michael, Jenewein, Brigitte, Trieb, Klemens, Grubeck-Loebenstein, Beatrix
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2017
Fag:
Immunology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5474847/
https://ncbi.nlm.nih.gov/pubmed/28674537
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.00715
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