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Overcoming the hurdles in using mouse genetic models that block TGF-β signaling

The recent recognition of the importance of transforming growth factor beta (TGF-β) in mediating many cellular immune functions has popularized the use of mouse models where TGF-β signaling is blocked in specific cell types. However, there are some caveats affiliated with each model. Here we describ...

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Detalhes bibliográficos
Main Authors: Sanjabi, Shomyseh, Flavell, Richard A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2845397/
https://ncbi.nlm.nih.gov/pubmed/20060833
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jim.2009.12.008
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