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The polarization of immune cells in the tumour environment by TGFβ

Transforming growth factor-β (TGFβ) is an immunosuppressive cytokine produced by tumour cells and immune cells that can polarize many arms of the immune system. This Review covers the effects of TGFβ on NK cells, dendritic cells, macrophages, neutrophils, CD8(+) and CD4(+) effector and regulatory ce...

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Main Authors: Flavell, Richard A., Sanjabi, Shomyseh, Wrzesinski, Stephen H., Licona-Limón, Paula
Formato: Artigo
Idioma:Inglês
Publicado: 2010
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3885992/
https://ncbi.nlm.nih.gov/pubmed/20616810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nri2808
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