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Lenalidomide at Therapeutic and Supratherapeutic Doses Does Not Prolong QTc Intervals in the Thorough QTc Study Conducted in Healthy Men

The effect of lenalidomide on the corrected QT (QTc) interval was evaluated in healthy men and extended to patients based on the lenalidomide concentration–QTc (C–QTc) relationship. A rigorous assessment of the effect of lenalidomide on QTc intervals was conducted in healthy volunteers who each rece...

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Bibliografske podrobnosti
Main Authors: Chen, Nianhang, Ye, Ying, Liu, Liangang, Reyes, Josephine, Assaf, Mahmoud S, Kasserra, Claudia, Zhou, Simon, Palmisano, Maria
Format: Artigo
Jezik:Inglês
Izdano: John Wiley & Sons 2013
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3884770/
https://ncbi.nlm.nih.gov/pubmed/23639045
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcpt.12081
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