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Lack of an Effect of Standard and Supratherapeutic Doses of Linezolid on QTc Interval Prolongation

A double-blind, placebo-controlled, four-way crossover study was conducted in 40 subjects to assess the effect of linezolid on corrected QT (QTc) interval prolongation. Time-matched, placebo-corrected QT intervals were determined predose and at 0.5, 1 (end of infusion), 2, 4, 8, 12, and 24 h after i...

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Main Authors: Damle, Bharat, LaBadie, Robert R., Cuozzo, Cheryl, Alvey, Christine, Choo, Heng Wee, Riley, Steve, Kirby, Deborah
格式: Artigo
語言:Inglês
出版: American Society for Microbiology 2011
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3165302/
https://ncbi.nlm.nih.gov/pubmed/21709083
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01723-10
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