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Lomitapide at Supratherapeutic Plasma Levels Does Not Prolong the QTc Interval—Results from a TQT Study with Moxifloxacin and Ketoconazole
BACKGROUND: The aim of this study was to assess the effect of high plasma levels of lomitapide and its main metabolite on ECG parameters. METHODS: In this randomized five‐way cross‐over thorough QT study, 56 healthy subjects were enrolled. Study treatments were administered orally for 3 days in five...
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| 出版年: | Ann Noninvasive Electrocardiol |
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| 主要な著者: | , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
John Wiley and Sons Inc.
2013
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6932020/ https://ncbi.nlm.nih.gov/pubmed/24118671 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/anec.12103 |
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