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Lenalidomide at Therapeutic and Supratherapeutic Doses Does Not Prolong QTc Intervals in the Thorough QTc Study Conducted in Healthy Men

The effect of lenalidomide on the corrected QT (QTc) interval was evaluated in healthy men and extended to patients based on the lenalidomide concentration–QTc (C–QTc) relationship. A rigorous assessment of the effect of lenalidomide on QTc intervals was conducted in healthy volunteers who each rece...

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Detalhes bibliográficos
Main Authors: Chen, Nianhang, Ye, Ying, Liu, Liangang, Reyes, Josephine, Assaf, Mahmoud S, Kasserra, Claudia, Zhou, Simon, Palmisano, Maria
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley & Sons 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3884770/
https://ncbi.nlm.nih.gov/pubmed/23639045
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcpt.12081
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