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Lenalidomide at Therapeutic and Supratherapeutic Doses Does Not Prolong QTc Intervals in the Thorough QTc Study Conducted in Healthy Men

The effect of lenalidomide on the corrected QT (QTc) interval was evaluated in healthy men and extended to patients based on the lenalidomide concentration–QTc (C–QTc) relationship. A rigorous assessment of the effect of lenalidomide on QTc intervals was conducted in healthy volunteers who each rece...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Chen, Nianhang, Ye, Ying, Liu, Liangang, Reyes, Josephine, Assaf, Mahmoud S, Kasserra, Claudia, Zhou, Simon, Palmisano, Maria
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley & Sons 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3884770/
https://ncbi.nlm.nih.gov/pubmed/23639045
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcpt.12081
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