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Neurodegenerative diseases and widespread aggregation are associated with supersaturated proteins
The maintenance of protein solubility is a fundamental aspect of protein homeostasis, as aggregation is associated with cytotoxicity and a variety of human diseases. Numerous proteins unrelated in sequence and structure, however, can misfold and aggregate, and widespread aggregation can occur in liv...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3883113/ https://ncbi.nlm.nih.gov/pubmed/24183671 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2013.09.043 |
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