Cornel Iridoid Glycoside Attenuates Tau Hyperphosphorylation by Inhibition of PP2A Demethylation

Aim. The aim of the present study was to investigate the effect of cornel iridoid glycoside (CIG) on tau hyperphosphorylation induced by wortmannin (WT) and GF-109203X (GFX) and the underlying mechanisms. Methods. Human neuroblastoma SK-N-SH cells were preincubated with CIG (50, 100, and 200 µg/ml,...

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Bibliografski detalji
Glavni autori: Yang, Cui-cui, Kuai, Xue-xian, Li, Ya-li, Zhang, Li, Yu, Jian-chun, Li, Lin, Zhang, Lan
Format: Artigo
Jezik:Inglês
Izdano: Hindawi Publishing Corporation 2013
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3880719/
https://ncbi.nlm.nih.gov/pubmed/24454482
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2013/108486
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