Cornel Iridoid Glycoside Attenuates Tau Hyperphosphorylation by Inhibition of PP2A Demethylation

Aim. The aim of the present study was to investigate the effect of cornel iridoid glycoside (CIG) on tau hyperphosphorylation induced by wortmannin (WT) and GF-109203X (GFX) and the underlying mechanisms. Methods. Human neuroblastoma SK-N-SH cells were preincubated with CIG (50, 100, and 200 µg/ml,...

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Main Authors: Yang, Cui-cui, Kuai, Xue-xian, Li, Ya-li, Zhang, Li, Yu, Jian-chun, Li, Lin, Zhang, Lan
Formato: Artigo
Idioma:Inglês
Publicado: Hindawi Publishing Corporation 2013
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3880719/
https://ncbi.nlm.nih.gov/pubmed/24454482
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2013/108486
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