Cornel iridoid glycoside ameliorates cognitive deficits in APP/PS1/tau triple transgenic mice by attenuating amyloid-beta, tau hyperphosphorylation and neurotrophic dysfunction

BACKGROUND: Targeted proteinopathy is involved in creating pharmacological agents that protect against Alzheimer disease (AD). Cornel iridoid glycoside (CIG) is an effective component derived from Cornus officinalis. The present study aimed to determine the effects of CIG on β-amyloid (Aβ) and tau p...

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Detalhes bibliográficos
Publicado no:Ann Transl Med
Main Authors: Yang, Cuicui, Bao, Xunjie, Zhang, Li, Li, Yali, Li, Lin, Zhang, Lan
Formato: Artigo
Idioma:Inglês
Publicado em: AME Publishing Company 2020
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7186687/
https://ncbi.nlm.nih.gov/pubmed/32355772
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21037/atm.2020.02.138
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