A carregar...
Targeting Botulinum A Cellular Toxicity: A Prodrug Approach
The botulinum neurotoxin light chain (LC) protease has become an important therapeutic target for post-exposure treatment of botulism. Hydroxamic acid based small molecules have proven to be potent inhibitors of LC/A with nanomolar K(i) values, yet, they lack cellular activity conceivably due to low...
Na minha lista:
| Main Authors: | , , , , , , , |
|---|---|
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3880648/ https://ncbi.nlm.nih.gov/pubmed/24127873 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm400873n |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|