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Metal Ions Effectively Ablate the Action of Botulinum Neurotoxin A

Botulinum neurotoxin serotype A (BoNT/A) causes a debilitating and potentially fatal illness known as botulism. The toxin is also a bioterrorism threat, yet no pharmacological antagonist to counteract its effects has reached clinical approval. Existing strategies to negate BoNT/A intoxication have l...

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書目詳細資料
發表在:J Am Chem Soc
Main Authors: Bremer, Paul T., Pellett, Sabine, Carolan, James P., Tepp, William H., Eubanks, Lisa M., Allen, Karen N., Johnson, Eric A., Janda, Kim D.
格式: Artigo
語言:Inglês
出版: 2017
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5612488/
https://ncbi.nlm.nih.gov/pubmed/28475321
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.7b01084
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