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Substrate Cleavage and Duration of Action of Botulinum Neurotoxin Type FA (“H, HA”)

Botulinum neurotoxin (BoNT) type FA is the only known naturally occurring chimeric BoNT of domains of BoNT/A and BoNT/F. BoNT/FA consists of an F5-like light chain (LC), a unique heavy chain (HC) translocation domain, and a HC receptor binding domain similar to BoNT/A1. Previous analyses of purified...

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Bibliografiske detaljer
Udgivet i:Toxicon
Main Authors: Pellett, Sabine, Tepp, William H., Lin, Guangyun, Johnson, Eric A.
Format: Artigo
Sprog:Inglês
Udgivet: 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5911199/
https://ncbi.nlm.nih.gov/pubmed/29273248
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.toxicon.2017.12.048
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