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Evaluation of the BH3-only Protein Puma as a Direct Bak Activator

Interactions among Bcl-2 family proteins play critical roles in cellular life and death decisions. Previous studies have established the BH3-only proteins Bim, tBid, and Noxa as “direct activators” that are able to directly initiate the oligomerization and activation of Bak and/or Bax. Earlier studi...

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Библиографические подробности
Главные авторы: Dai, Haiming, Pang, Yuan-Ping, Ramirez-Alvarado, Marina, Kaufmann, Scott H.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Biochemistry and Molecular Biology 2014
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3879582/
https://ncbi.nlm.nih.gov/pubmed/24265320
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.505701
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