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Structural Aspects of GPCR-G Protein Coupling
G protein-coupled receptors (GPCRs) are membrane receptors; approximately 40% of drugs on the market target GPCRs. A precise understanding of the activation mechanism of GPCRs would facilitate the development of more effective and less toxic drugs. Heterotrimeric G proteins are important molecular s...
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| Главный автор: | |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
The Korean Society of Toxicology
2013
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3877993/ https://ncbi.nlm.nih.gov/pubmed/24386514 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5487/TR.2013.29.3.149 |
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