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CK2 Controls Multiple Protein Kinases by Phosphorylating a Kinase-Targeting Molecular Chaperone, Cdc37

Cdc37 is a kinase-associated molecular chaperone whose function in concert with Hsp90 is essential for many signaling protein kinases. Here, we report that mammalian Cdc37 is a pivotal substrate of CK2 (casein kinase II). Purified Cdc37 was phosphorylated in vitro on a conserved serine residue, Ser1...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Mol Cell Biol
Hauptverfasser: Miyata, Yoshihiko, Nishida, Eisuke
Format: Artigo
Sprache:Inglês
Veröffentlicht: Taylor & Francis 2004
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC387775/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15082798/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.24.9.4065-4074.2004
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