Serine/Threonine Kinase Unc-51-like Kinase-1 (Ulk1) Phosphorylates the Co-chaperone Cell Division Cycle Protein 37 (Cdc37) and Thereby Disrupts the Stability of Cdc37 Client Proteins

The serine/threonine kinase Unc-51-like kinase-1 (Ulk1) is thought to be essential for induction of autophagy, an intracellular bulk degradation process that is activated by various stresses. Although several proteins have been suggested as Ulk1 substrates during autophagic process, it still remains...

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Foilsithe in:J Biol Chem
Main Authors: Li, Ran, Yuan, Fengjie, Fu, Wan, Zhang, Luyao, Zhang, Nan, Wang, Yanan, Ma, Ke, Li, Xue, Wang, Lina, Zhu, Wei-Guo, Zhao, Ying
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Biochemistry and Molecular Biology 2017
Ábhair:
Cell Biology
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5314178/
https://ncbi.nlm.nih.gov/pubmed/28073914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.762443
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