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Cdc37 Promotes the Stability of Protein Kinases Cdc28 and Cak1

In the budding yeast Saccharomyces cerevisiae, Cdc37 is required for the productive formation of Cdc28-cyclin complexes. The cdc37-1 mutant arrests at Start with low levels of Cdc28 protein, which is predominantly unphosphorylated at Thr169, fails to bind cyclin, and has little protein kinase activi...

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Détails bibliographiques
Auteurs principaux: Farrell, Alison, Morgan, David O.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2000
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC85190/
https://ncbi.nlm.nih.gov/pubmed/10629030
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