The Molecular Chaperone TRiC/CCT Binds to the Trp-Asp 40 (WD40) Repeat Protein WDR68 and Promotes Its Folding, Protein Kinase DYRK1A Binding, and Nuclear Accumulation

Trp-Asp (WD) repeat protein 68 (WDR68) is an evolutionarily conserved WD40 repeat protein that binds to several proteins, including dual specificity tyrosine phosphorylation-regulated protein kinase (DYRK1A), MAPK/ERK kinase kinase 1 (MEKK1), and Cullin4-damage-specific DNA-binding protein 1 (CUL4-D...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Miyata, Yoshihiko, Shibata, Takeshi, Aoshima, Masato, Tsubata, Takuichi, Nishida, Eisuke
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2014
Assuntos:
Cell Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4246089/
https://ncbi.nlm.nih.gov/pubmed/25342745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.586115
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