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The WD40 Repeat Protein WDR26 Binds Gβγ and Promotes Gβγ-dependent Signal Transduction and Leukocyte Migration

The Gβγ subunits of heterotrimeric G proteins transmit signals to control many cellular processes, including leukocyte migration. Gβγ signaling may regulate and be regulated by numerous signaling partners. Here, we reveal that WDR26, a member of the WD40 repeat protein family, directly bound free Gβ...

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Détails bibliographiques
Auteurs principaux: Sun, Zhizeng, Tang, Xiaoyun, Lin, Fang, Chen, Songhai
Format: Artigo
Langue:Inglês
Publié: American Society for Biochemistry and Molecular Biology 2011
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3243526/
https://ncbi.nlm.nih.gov/pubmed/22065575
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.301382
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