A Novel Function of the MA-3 Domains in Transformation and Translation Suppressor Pdcd4 Is Essential for Its Binding to Eukaryotic Translation Initiation Factor 4A

Αn α-helical MA-3 domain appears in several translation initiation factors, including human eukaryotic translation initiation factor 4G (eIF4G) and DAP-5/NAT1/p97, as well as in the tumor suppressor Pdcd4. The function of the MA-3 domain is, however, unknown. C-terminal eIF4G (eIG4Gc) contains an MA...

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Bibliographische Detailangaben
Hauptverfasser: Yang, Hsin-Sheng, Cho, Myung-Haing, Zakowicz, Halina, Hegamyer, Glenn, Sonenberg, Nahum, Colburn, Nancy H.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2004
Schlagworte:
Cell Growth and Development
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC387765/
https://ncbi.nlm.nih.gov/pubmed/15082783
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.9.3894-3906.2004
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