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Structural Basis for Inhibition of Translation by the Tumor Suppressor Pdcd4
The tumor suppressor function of Programmed Cell Death 4 (Pdcd4) is achieved through interactions between Pdcd4 and components of the translation initiation complex, namely, the RNA helicase eIF4A and the scaffolding protein eIF4G. These interactions are mediated through two MA3 domains on the Pdcd4...
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| Hlavní autoři: | , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
American Society for Microbiology
2007
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1800662/ https://ncbi.nlm.nih.gov/pubmed/17060447 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00867-06 |
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