Novel somatic mutations in large granular lymphocytic leukemia affecting the STAT-pathway and T-cell activation

T-cell large granular lymphocytic (T-LGL) leukemia is a clonal disease characterized by the expansion of mature CD3+CD8+ cytotoxic T cells. It is often associated with autoimmune disorders and immune-mediated cytopenias. Our recent findings suggest that up to 40% of T-LGL patients harbor mutations i...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Andersson, E I, Rajala, H L M, Eldfors, S, Ellonen, P, Olson, T, Jerez, A, Clemente, M J, Kallioniemi, O, Porkka, K, Heckman, C, Loughran, T P, Maciejewski, J P, Mustjoki, S
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2013
Témata:
Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3877422/
https://ncbi.nlm.nih.gov/pubmed/24317090
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bcj.2013.65
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky