Fragment-based design for the development of N-domain-selective angiotensin-1-converting enzyme inhibitors

ACE (angiotensin-1-converting enzyme) is a zinc metallopeptidase that plays a prominent role in blood pressure regulation and electrolyte homeostasis. ACE consists of two homologous domains that despite similarities of sequence and topology display differences in substrate processing and inhibitor b...

Descripció completa

Guardat en:
Dades bibliogràfiques
Autors principals: Douglas, Ross G., Sharma, Rajni K., Masuyer, Geoffrey, Lubbe, Lizelle, Zamora, Ismael, Acharya, K. Ravi, Chibale, Kelly, Sturrock, Edward D.
Format: Artigo
Idioma:Inglês
Publicat: Portland Press Ltd. 2013
Matèries:
Original Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3875237/
https://ncbi.nlm.nih.gov/pubmed/24015848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/CS20130403
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars