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Susceptibility to CD8 T cell-mediated killing influences the reservoir of latently HIV-1 infected CD4 T cells

BACKGROUND: HIV-1 establishes a life-long infection in the human body, but host factors that influence viral persistence remain poorly understood. Cell-intrinsic characteristics of CD4 T cells, the main target cells for HIV-1, may impact the composition of the latent viral reservoir by altering the...

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Main Authors: Buzon, Maria J., Yang, Yue, Ouyang, Zhengyu, Sun, Hong, Seiss, Katherine, Rogich, Jerome, Le Gall, Sylvie, Pereyra, Florencia, Rosenberg, Eric S., Yu, Xu G., Lichterfeld, Mathias
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2014
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3874432/
https://ncbi.nlm.nih.gov/pubmed/23846565
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/QAI.0b013e3182a1bc81
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