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Inhibition of HIV-1 Integration in Ex Vivo-Infected CD4 T Cells from Elite Controllers

Elite controllers spontaneously maintain undetectable levels of HIV-1 replication for reasons that remain unclear. Here, we show that in elite controllers, direct ex vivo infection of purified CD4 T cells without prior in vitro activation results in disproportionately low levels of integrated HIV-1...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Buzon, Maria J., Seiss, Katherine, Weiss, Robert, Brass, Abraham L., Rosenberg, Eric S., Pereyra, Florencia, Yu, Xu G., Lichterfeld, Mathias
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3165766/
https://ncbi.nlm.nih.gov/pubmed/21734042
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.05327-11
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