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Shelterin Dysfunction and p16(INK4a)-Mediated Growth Inhibition in HIV-1-Specific CD8 T Cells
HIV-1-specific cytotoxic T cell responses are expanded during advanced HIV-1 infection but seem unable to effectively protect the host against disease progression. These cells are able to produce gamma interferon and remain metabolically active but have defective proliferative activities, shortened...
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| Hoofdauteurs: | , , , , , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
American Society for Microbiology
2012
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3347267/ https://ncbi.nlm.nih.gov/pubmed/22398292 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00196-12 |
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