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Epigenetic regulation of telomerase expression in HIV-1-specific CD8+ T cells
Telomerase activity in HIV-1-specific CD8+ T cells from controllers contributes to the maintenance of highly-functional cytotoxic T cell responses against HIV-1. Here, we show that high expression of telomerase in controllers is associated with hypermethylation at the distal and hypomethylation at t...
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| Главные авторы: | , , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2010
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2924203/ https://ncbi.nlm.nih.gov/pubmed/20588158 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/QAD.0b013e32833c7170 |
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