Epigenetic regulation of telomerase expression in HIV-1-specific CD8+ T cells

Telomerase activity in HIV-1-specific CD8+ T cells from controllers contributes to the maintenance of highly-functional cytotoxic T cell responses against HIV-1. Here, we show that high expression of telomerase in controllers is associated with hypermethylation at the distal and hypomethylation at t...

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Bibliographic Details
Main Authors: Williams, Katie, Seiss, Katherine, Beamon, Jill, Pereyra, Florencia, Rosenberg, Eric S., Walker, Bruce D., Yu, Xu G., Lichterfeld, Mathias
Format: Artigo
Language:Inglês
Published: 2010
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2924203/
https://ncbi.nlm.nih.gov/pubmed/20588158
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/QAD.0b013e32833c7170
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