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Unfolding Simulations of Holomyoglobin from Four Mammals: Identification of Intermediates and β-Sheet Formation from Partially Unfolded States

Myoglobin (Mb) is a centrally important, widely studied mammalian protein. While much work has investigated multi-step unfolding of apoMb using acid or denaturant, holomyoglobin unfolding is poorly understood despite its biological relevance. We present here the first systematic unfolding simulation...

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Bibliografski detalji
Glavni autori: Dasmeh, Pouria, Kepp, Kasper P.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2013
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3873898/
https://ncbi.nlm.nih.gov/pubmed/24386077
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0080308
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