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A Model of Proteostatic Energy Cost and Its Use in Analysis of Proteome Trends and Sequence Evolution
A model of proteome-associated chemical energetic costs of cells is derived from protein-turnover kinetics and protein folding. Minimization of the proteostatic maintenance cost can explain a range of trends of proteomes and combines both protein function, stability, size, proteostatic cost, tempera...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Public Library of Science
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3938754/ https://ncbi.nlm.nih.gov/pubmed/24587382 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0090504 |
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