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A Model of Proteostatic Energy Cost and Its Use in Analysis of Proteome Trends and Sequence Evolution

A model of proteome-associated chemical energetic costs of cells is derived from protein-turnover kinetics and protein folding. Minimization of the proteostatic maintenance cost can explain a range of trends of proteomes and combines both protein function, stability, size, proteostatic cost, tempera...

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Detalhes bibliográficos
Main Authors: Kepp, Kasper P., Dasmeh, Pouria
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3938754/
https://ncbi.nlm.nih.gov/pubmed/24587382
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0090504
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