A High-Fat Diet Activates Oncogenic Kras and COX2 to Induce Development of Pancreatic Ductal Adenocarcinoma in Mice

BACKGROUND & AIMS: Obesity is a risk factor for pancreatic ductal adenocarcinoma (PDAC), but it is not clear how obesity contributes to pancreatic carcinogenesis. The oncogenic form of KRAS is expressed during early stages of PDAC development, and is detected in almost all of these tumors. Howev...

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Detaylı Bibliyografya
Asıl Yazarlar: Philip, Bincy, Roland, Christina L., Daniluk, Jaroslaw, Liu, Yan, Chatterjee, Deyali, Gomez, Sobeyda B., Ji, Baoan, Huang, Haojie, Wang, Huamin, Fleming, Jason B., Logsdon, Craig D., Cruz-Monserrate, Zobeida
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2013
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Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3873752/
https://ncbi.nlm.nih.gov/pubmed/23958541
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2013.08.018
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