Lipocalin-2 Promotes Pancreatic Ductal Adenocarcinoma by Regulating Inflammation in the Tumor Microenvironment

Lipocalin-2 (LCN2) promotes malignant development in many cancer types. LCN2 is upregulated in patients with pancreatic ductal adenocarcinoma (PDAC) and in obese individuals, but whether it contributes to PDAC development is unclear. In this study, we investigated the effects of Lcn2 depletion on di...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Cancer Res
Prif Awduron: Gomez-Chou, Sobeyda B., Swidnicka-Siergiejko, Agnieszka Katarzyna, Badi, Niharika, Chavez-Tomar, Myrriah, Lesinski, Gregory B., Bekaii-Saab, Tanios, Farren, Matthew R., Mace, Thomas A., Schmidt, Carl, Liu, Yan, Deng, Defeng, Hwang, Rosa F., Zhou, Liran, Moore, Todd, Chatterjee, Deyali, Wang, Huamin, Leng, Xiaohong, Arlinghaus, Ralph B., Logsdon, Craig D., Cruz-Monserrate, Zobeida
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2017
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5441230/
https://ncbi.nlm.nih.gov/pubmed/28249896
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-16-1986
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