Circulating Interleukin-6 is Associated with Disease Progression, but not Cachexia in Pancreatic Cancer

BACKGROUND: Cachexia is a wasting syndrome characterized by involuntary loss of >5% body weight due to depletion of adipose and skeletal muscle mass. In cancer, the pro-inflammatory cytokine interleukin-6 (IL-6) is considered a mediator of cachexia and a potential biomarker, but the relationship...

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Publicado no:Pancreatology
Main Authors: Ramsey, Mitchell L., Talbert, Erin, Ahn, Daniel, Bekaii-Saab, Tanios, Badi, Niharika, Bloomston, P. Mark, Conwell, Darwin L., Cruz-Monserrate, Zobeida, Dillhoff, Mary, Farren, Matthew R., Hinton, Alice, Krishna, Somashekar G., Lesinski, Gregory B., Mace, Thomas, Manilchuk, Andrei, Noonan, Anne, Pawlik, Timothy M., Rajasekera, Priyani V., Schmidt, Carl, Guttridge, Denis, Hart, Phil A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6613190/
https://ncbi.nlm.nih.gov/pubmed/30497874
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pan.2018.11.002
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