Preclinical Investigation of the Novel Histone Deacetylase Inhibitor AR-42 in the Treatment of Cancer-Induced Cachexia

BACKGROUND: Cancer cachexia is a debilitating condition that impacts patient morbidity, mortality, and quality of life and for which effective therapies are lacking. The anticachectic activity of the novel HDAC inhibitor AR-42 was investigated in murine models of cancer cachexia. METHODS: The effect...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:J Natl Cancer Inst
Main Authors: Tseng, Yu-Chou, Kulp, Samuel K., Lai, I-Lu, Hsu, En-Chi, He, Wei A., Frankhouser, David E., Yan, Pearlly S., Mo, Xiaokui, Bloomston, Mark, Lesinski, Gregory B., Marcucci, Guido, Guttridge, Denis C., Bekaii-Saab, Tanios, Chen, Ching-Shih
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2015
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6280990/
https://ncbi.nlm.nih.gov/pubmed/26464423
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jnci/djv274
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados