Loss of Notch1 activity inhibits prostate cancer growth and metastasis and sensitizes prostate cancer cells to anti-androgen therapies

Por Rice, Meghan A., Hsu, En-Chi, Aslan, Merve, Ghoochani, Ali, Su, Austin, Stoyanova, Tanya
Publicado no Mol Cancer Ther (2019)

Identification and Characterization of a Novel Integrin-Linked Kinase Inhibitor

Por Lee, Su-Lin, Hsu, En-Chi, Chou, Chih-Chien, Chuang, Hsiao-Ching, Bai, Li-Yuan, Kulp, Samuel K., Chen, Ching-Shih
Publicado em 2011

Targeting Energy Metabolic and Oncogenic Signaling Pathways in Triple-negative Breast Cancer by a Novel Adenosine Monophosphate-activated Protein Kinase (AMPK) Activator

Por Lee, Kuen-Haur, Hsu, En-Chi, Guh, Jih-Hwa, Yang, Hsiao-Ching, Wang, Dasheng, Kulp, Samuel K., Shapiro, Charles L., Chen, Ching-Shih
Publicado em 2011

Functional Role of mTORC2 versus Integrin-Linked Kinase in Mediating Ser473-Akt Phosphorylation in PTEN-Negative Prostate and Breast Cancer Cell Lines

Por Lee, Su-Lin, Chou, Chih-Chien, Chuang, Hsiao-Ching, Hsu, En-Chi, Chiu, Po-Chen, Kulp, Samuel K., Byrd, John C., Chen, Ching-Shih
Publicado em 2013

Function of Integrin-Linked Kinase in Modulating the Stemness of IL-6–Abundant Breast Cancer Cells by Regulating γ-Secretase–Mediated Notch1 Activation in Caveolae()()

Por Hsu, En-Chi, Kulp, Samuel K., Huang, Han-Li, Tu, Huang-Ju, Salunke, Santosh B., Sullivan, Nicholas J., Sun, Duxin, Wicha, Max S., Shapiro, Charles L., Chen, Ching-Shih
Publicado no Neoplasia (2015)

PSPC1-interchanged interactions with PTK6 and β-catenin synergize oncogenic subcellular translocations and tumor progression

Por Lang, Yaw-Dong, Chen, Hsin-Yi, Ho, Chun-Ming, Shih, Jou-Ho, Hsu, En-Chi, Shen, Roger, Lee, Yu-Ching, Chen, Jyun-Wei, Wu, Cheng-Yen, Yeh, Hsi-Wen, Chen, Ruey-Hwa, Jou, Yuh-Shan
Publicado no Nat Commun (2019)

Non-epigenetic function of HDAC8 in regulating breast cancer stem cells by maintaining Notch1 protein stability

Por Chao, Min-Wu, Chu, Po-Chen, Chuang, Hsiao-Ching, Shen, Fang-Hsiu, Chou, Chih-Chien, Hsu, En-Chi, Himmel, Lauren E., Huang, Han-Li, Tu, Huang-Ju, Kulp, Samuel K., Teng, Che-Ming, Chen, Ching-Shih
Publicado no Oncotarget (2015)

Retraction: Non-epigenetic function of HDAC8 in regulating breast cancer stem cells by maintaining Notch1 protein stability

Por Chao, Min-Wu, Chu, Po-Chen, Chuang, Hsiao-Ching, Shen, Fang-Hsiu, Chou, Chih-Chien, Hsu, En-Chi, Himmel, Lauren E., Huang, Han-Li, Tu, Huang-Ju, Kulp, Samuel K., Teng, Che-Ming, Chen, Ching-Shih
Publicado no Oncotarget (2020)

Discovery of PTN as a serum-based biomarker of pro-metastatic prostate cancer

Por Liu, Shiqin, Shen, Michelle, Hsu, En-Chi, Zhang, Chiyuan Amy, Garcia-Marques, Fernando, Nolley, Rosalie, Koul, Kashyap, Rice, Meghan A., Aslan, Merve, Pitteri, Sharon J., Massie, Charlie, George, Anne, Brooks, James D., Gnanapragasam, Vincent J., Stoyanova, Tanya
Publicado no Br J Cancer (2020)

Preclinical Investigation of the Novel Histone Deacetylase Inhibitor AR-42 in the Treatment of Cancer-Induced Cachexia

Por Tseng, Yu-Chou, Kulp, Samuel K., Lai, I-Lu, Hsu, En-Chi, He, Wei A., Frankhouser, David E., Yan, Pearlly S., Mo, Xiaokui, Bloomston, Mark, Lesinski, Gregory B., Marcucci, Guido, Guttridge, Denis C., Bekaii-Saab, Tanios, Chen, Ching-Shih
Publicado no J Natl Cancer Inst (2015)

Integrin-linked kinase as a novel molecular switch of the IL-6-NF-κB signaling loop in breast cancer

Por Hsu, En-Chi, Kulp, Samuel K., Huang, Han-Li, Tu, Huang-Ju, Chao, Min-Wu, Tseng, Yu-Chou, Yang, Ming-Chen, Salunke, Santosh B., Sullivan, Nicholas J., Chen, Wen-Chung, Zhang, Jianying, Teng, Che-Ming, Fu, Wen-Mei, Sun, Duxin, Wicha, Max S., Shapiro, Charles L., Chen, Ching-Shih
Publicado no Carcinogenesis (2016)

The Exosome Total Isolation Chip

Por Liu, Fei, Vermesh, Ophir, Mani, Vigneshwaran, Ge, Tianjia J., Madsen, Steven J., Sabour, Andrew, Hsu, En-Chi, Gowrishankar, Gayatri, Kanada, Masamitsu, Jokerst, Jesse V., Sierra, Raymond G., Chang, Edwin, Lau, Kenneth, Sridhar, Kaushik, Bermudez, Abel, Pitteri, Sharon J., Stoyanova, Tanya, Sinclair, Robert, Nair, Viswam S., Gambhir, Sanjiv S., Demirci, Utkan
Publicado no ACS Nano (2017)

Trop2 is a driver of metastatic prostate cancer with neuroendocrine phenotype via PARP1

Por Hsu, En-Chi, Rice, Meghan A., Bermudez, Abel, Marques, Fernando Jose Garcia, Aslan, Merve, Liu, Shiqin, Ghoochani, Ali, Zhang, Chiyuan Amy, Chen, Yun-Sheng, Zlitni, Aimen, Kumar, Sahil, Nolley, Rosalie, Habte, Frezghi, Shen, Michelle, Koul, Kashyap, Peehl, Donna M., Zoubeidi, Amina, Gambhir, Sanjiv S., Kunder, Christian A., Pitteri, Sharon J., Brooks, James D., Stoyanova, Tanya
Publicado no Proc Natl Acad Sci U S A (2020)

Activation of Notch1 synergizes with multiple pathways in promoting castration-resistant prostate cancer

Por Stoyanova, Tanya, Riedinger, Mireille, Lin, Shu, Faltermeier, Claire M., Smith, Bryan A., Zhang, Kelvin X., Going, Catherine C., Goldstein, Andrew S., Lee, John K., Drake, Justin M., Rice, Meghan A., Hsu, En-Chi, Nowroozizadeh, Behdokht, Castor, Brandon, Orellana, Sandra Y., Blum, Steven M., Cheng, Donghui, Pienta, Kenneth J., Reiter, Robert E., Pitteri, Sharon J., Huang, Jiaoti, Witte, Owen N.
Publicado no Proc Natl Acad Sci U S A (2016)