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Synergy of Histone-Deacetylase Inhibitor AR-42 with Cisplatin in Bladder Cancer

PURPOSE: Cisplatin based chemotherapy regimens form the basis of systemic bladder cancer treatment, although they show limited response rates and efficacy. Recent molecular analysis of bladder cancer revealed a high incidence of mutations in chromatin regulatory genes, suggesting a therapeutic avenu...

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Bibliographic Details
Published in:J Urol
Main Authors: Li, David R., Zhang, Hanwei, Peek, Elizabeth, Wang, Song, Du, Lin, Li, Gang, Chin, Arnold I.
Format: Artigo
Language:Inglês
Published: 2015
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6371809/
https://ncbi.nlm.nih.gov/pubmed/25748177
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.juro.2015.02.2918
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