Lipocalin-2 Promotes Pancreatic Ductal Adenocarcinoma by Regulating Inflammation in the Tumor Microenvironment

Lipocalin-2 (LCN2) promotes malignant development in many cancer types. LCN2 is upregulated in patients with pancreatic ductal adenocarcinoma (PDAC) and in obese individuals, but whether it contributes to PDAC development is unclear. In this study, we investigated the effects of Lcn2 depletion on di...

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Bibliografske podrobnosti
izdano v:Cancer Res
Main Authors: Gomez-Chou, Sobeyda B., Swidnicka-Siergiejko, Agnieszka Katarzyna, Badi, Niharika, Chavez-Tomar, Myrriah, Lesinski, Gregory B., Bekaii-Saab, Tanios, Farren, Matthew R., Mace, Thomas A., Schmidt, Carl, Liu, Yan, Deng, Defeng, Hwang, Rosa F., Zhou, Liran, Moore, Todd, Chatterjee, Deyali, Wang, Huamin, Leng, Xiaohong, Arlinghaus, Ralph B., Logsdon, Craig D., Cruz-Monserrate, Zobeida
Format: Artigo
Jezik:Inglês
Izdano: 2017
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5441230/
https://ncbi.nlm.nih.gov/pubmed/28249896
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-16-1986
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