Performance of Common Analysis Methods for Detecting Low-Frequency Single Nucleotide Variants in Targeted Next-Generation Sequence Data

Next-generation sequencing (NGS) is becoming a common approach for clinical testing of oncology specimens for mutations in cancer genes. Unlike inherited variants, cancer mutations may occur at low frequencies because of contamination from normal cells or tumor heterogeneity and can therefore be cha...

Descrición completa

Gardado en:
Detalles Bibliográficos
Main Authors: Spencer, David H., Tyagi, Manoj, Vallania, Francesco, Bredemeyer, Andrew J., Pfeifer, John D., Mitra, Rob D., Duncavage, Eric J.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Investigative Pathology 2014
Assuntos:
Regular Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3873500/
https://ncbi.nlm.nih.gov/pubmed/24211364
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmoldx.2013.09.003
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares