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SNVHMM: predicting single nucleotide variants from next generation sequencing

BACKGROUND: The rapid development of next generation sequencing (NGS) technology provides a novel avenue for genomic exploration and research. Single nucleotide variants (SNVs) inferred from next generation sequencing are expected to reveal gene mutations in cancer. However, NGS has lower sequence c...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Bian, Jiawen, Liu, Chenglin, Wang, Hongyan, Xing, Jing, Kachroo, Priyanka, Zhou, Xiaobo
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3718670/
https://ncbi.nlm.nih.gov/pubmed/23855743
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-14-225
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