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hERG Potassium Channel Blockage by Scorpion Toxin BmKKx2 Enhances Erythroid Differentiation of Human Leukemia Cells K562

BACKGROUND: The hERG potassium channel can modulate the proliferation of the chronic myelogenous leukemic K562 cells, and its role in the erythroid differentiation of K562 cells still remains unclear. PRINCIPAL FINDINGS: The hERG potassium channel blockage by a new 36-residue scorpion toxin BmKKx2,...

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Main Authors: Ma, Jian, Hu, Youtian, Guo, Mingxiong, Huang, Zan, Li, Wenxin, Wu, Yingliang
格式: Artigo
語言:Inglês
出版: Public Library of Science 2013
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3873423/
https://ncbi.nlm.nih.gov/pubmed/24386436
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0084903
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