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Apelin-13 Inhibits Large-Conductance Ca(2+)-Activated K(+) Channels in Cerebral Artery Smooth Muscle Cells via a PI3-Kinase Dependent Mechanism
Apelin-13 causes vasoconstriction by acting directly on APJ receptors in vascular smooth muscle (VSM) cells; however, the ionic mechanisms underlying this action at the cellular level remain unclear. Large-conductance Ca(2+)-activated K(+) (BK(Ca)) channels in VSM cells are critical regulators of me...
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| Главные авторы: | , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Public Library of Science
2013
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3873301/ https://ncbi.nlm.nih.gov/pubmed/24386141 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0083051 |
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