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Apelin Reduces Nitric Oxide-Induced Relaxation of Cerebral Arteries by Inhibiting Activation of Large Conductance, Calcium-Activated K Channels

Activation of the apelin/APJ receptor signaling system causes endothelium- and nitric oxide (NO)-dependent relaxation in several peripheral arteries. The effects of apelin in cerebral arteries are unknown; however, apelin inhibits voltage-dependent increases in large-conductance, calcium-activated K...

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Detalhes bibliográficos
Publicado no:J Cardiovasc Pharmacol
Main Authors: Mughal, Amreen, Sun, Chengwen, O’Rourke, Stephen T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5890950/
https://ncbi.nlm.nih.gov/pubmed/29620606
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/FJC.0000000000000563
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