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Apelin Does Not Impair Coronary Artery Relaxation Mediated by Nitric Oxide-Induced Activation of BK(Ca) Channels

Apelin-APJ receptor signaling regulates vascular tone in cerebral and peripheral arteries. We recently reported that apelin inhibits BK(Ca) channel function in cerebral arteries, resulting in impaired endothelium-dependent relaxations. In contrast, apelin causes endothelium-dependent relaxation of c...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Mughal, Amreen, Sun, Chengwen, O’Rourke, Stephen T.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8194342/
https://ncbi.nlm.nih.gov/pubmed/34122102
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2021.679005
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