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Pressor Effect of Apelin-13 in the Rostral Ventrolateral Medulla: Role of NAD(P)H Oxidase-Derived Superoxide

Microinjection of apelin-13 into the rostral ventrolateral medulla (RVLM) in the brainstem increases blood pressure in rats. In the present study, we tested the hypotheses that apelin-13 directly stimulates neuronal activity in neurons cultured from the brainstem and that NAD(P)H oxidase-derived rea...

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Detalhes bibliográficos
Main Authors: Yao, Fanrong, Modgil, Amit, Zhang, Qi, Pingili, Ajeeth, Singh, Neha, O'Rourke, Stephen T., Sun, Chengwen
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Pharmacology and Experimental Therapeutics 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3033721/
https://ncbi.nlm.nih.gov/pubmed/21047952
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.110.174102
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