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Cytometric Analysis of DNA Damage: Phosphorylation of Histone H2AX as a Marker of DNA Double-Strand Breaks (DSBs)

Phosphorylation of histone H2AX on Ser 139 is a sensitive reporter of DNA damage, particularly if the damage involves induction of DNA double-strand breaks (DSBs). Phosphorylated H2AX has been named γH2AX and its presence in the nucleus can be detected immunocytochemically. Multiparameter analysis o...

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Hlavní autoři: Tanaka, Toshiki, Halicka, Dorota, Traganos, Frank, Darzynkiewicz, Zbigniew
Médium: Artigo
Jazyk:Inglês
Vydáno: 2009
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3872964/
https://ncbi.nlm.nih.gov/pubmed/19381940
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-59745-190-1_11
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